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Identification of a human multipotent TH2 progenitor
In this study, we use a transcriptomic approach as a starting point to explore the heterogeneity of human GATA3-expressing lymphocytes across different tissues and disease contexts. We identify, characterize and functionally validate an abundant progenitor-like memory T cell population with the potential to sustain pathogenic TH2 cell inflammation.
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Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection
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SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
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Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease
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An IL-1β-driven neutrophil–stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma